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3D打印技术正改变着整个人类的工业进程，使得制造业由传统的“流水线”车间化生产变为“个体化”多点制造。医疗领域同样见证了这一改变，主要体现在骨科、口腔科及放射科等多个临床科室，尤其在肿瘤放疗中的作用日益凸显。目前研究和应用热点主要集中于外照射(个体化3D打印组织补偿物、个体化3D打印模体、个体化固定装置)与内照射(后装和粒子植入治疗)，现结合国内外进展分别做一综述。“,”Three-dimensional (3D) printing technique has been improving the industrial process from uniform pipeline production procedure in manufacture into individualized production with distributed network. 3D printing technique also provokes these changes in the field of medicine, especially in orthopedics, stomatology and radiology. The role of 3D printing technique has been increasingly highlighted in tumor radiotherapy. Current studies and application mainly focus on personalized tissue compensato (bolus), brachytherapy (high-dose post-loading and particle implantation therapy), 3D printing personalized phantom and individualized fixtures, etc. In this article, research progresses on the application of 3D printing technique in radiotherapy at home and abroad were reviewed.