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目的:应用 Amplatzer 血管塞封堵动脉导管未闭(PDA)并对其疗效进行评价。方法:全组共11例,年龄4.0～17.0(10.09±5.17)岁,体重15～63(35.05±16.20)kg。PDA 长度为8.4～20.9(14.09±3.50)mm,最狭窄处均位于肺动脉侧,直径为1.0～2.0(1.48±0.35)mm;经导管置入 Amplatzer 血管塞封堵PDA。封堵后5～10 min 行胸主动脉造影评价疗效,术后24 h、1个月、3个月及1年进行随访观察有无残余分流及再通。结果:全组技术成功率为100%,无任何并发症。术后10 min 胸主动脉造影示11例动脉导管均完全闭合,无残余分流;5例完成1年随访,PDA 完全闭合,未见再通。结论:应用 Amplatzer 血管寨封堵类似于长管状的 PDA 是一种安全、有效的非手术方法,技术成功率高,即刻效果好,近、中远期随访疗效可靠。
OBJECTIVE: To evaluate the efficacy of Amplatzer vessel occlusion of patent ductus arteriosus (PDA). Methods: The whole group consisted of 11 patients aged 4.0-17.0 (10.09 ± 5.17) years and weighing 15-63 (35.05 ± 16.20) kg. The length of PDA ranged from 8.4 to 20.9 (14.09 ± 3.50) mm, with the narrowest point located on the pulmonary artery with a diameter of 1.0 to 2.0 (1.48 ± 0.35) mm. PDA was catheterized by Amplatzer vasoconstrictor. The effect of thoracic aorta angiography was evaluated 5 to 10 minutes after occlusion, and the residual shunts and recanalization were observed at 24 h, 1 month, 3 months and 1 year after operation. Results: The technical success rate of the whole group was 100% without any complications. Thoracic aorta angiography at 10 min showed complete closure of 11 cases of patent ductus arteriosus without residual shunt; 5 cases completed 1 year follow-up, PDA completely closed, no recanalization. CONCLUSION: Amplatzer is a safe and effective non-surgical method to seal a PDA with long tubular shape. It has high technical success rate and good immediate effect. The follow-up of long-term and long-term efficacy is reliable.