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对于哺乳动物嗜肝DNA病毒基因组x区域第四个也是最小的开读框架(OPF)的了解甚微,据知在人或土拨鼠感染期间,这个区域呈现表答,即产生抗x基因产物的抗体。最近的研究表明x基因产物起转录激活因子的作用。
Little is known about the fourth and the smallest open reading frame (OPF) in the x-region of the mammalian hepadnavirus genome, and it is known that this region presents an epigenetic response during human or woodchuck infection that produces an anti-x-gene product Antibody. Recent studies have shown that x gene products act as transcriptional activators.