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异烟肼是水溶性药物,制成乙基纤维素微囊骨架具有缓慢释药、高剂量、无毒性反应的特征。然后制成片剂,达到良好的缓释效果。本文研究了异烟肼乙基纤维素微囊的四种制备工艺对释药速度的影响并进行体外溶解实验研究。
Isoniazid is a water-soluble drug, made of ethyl cellulose microcapsule skeleton has a slow release, high-dose, non-toxic reaction characteristics. Then made into tablets, to achieve good sustained release effect. In this paper, the effects of four preparation processes of isoniazid ethylcellulose microcapsules on drug release rate were studied and in vitro dissolution experiments were carried out.