1例48岁女性接种四价流感病毒裂解疫苗，7 d后甲状腺左侧出现压痛及触痛性包块，诊断为亚急性甲状腺炎。予塞来昔布胶囊200 mg口服、2次/d，外敷平瘿散，内服中药汤剂。21 d后疼痛和包块消失。1周后患者甲状腺右侧出现类似症状，再次服用相同剂量塞来昔布胶囊，无效，换用醋酸泼尼松片20 mg口服、1次/d。25 d后疼痛缓解，颈部包块缩小。考虑患者的亚急性甲状腺炎可能为四价流感病毒裂解疫苗所致。“,”A 48-year-old woman was vaccinated with quadrivalent lytic influenza virus vaccine. Seven days later, tenderness pain and mass with tenderness pain appeared on the left side of the thyroid gland, which was diagnosed as subacute thyroiditis. The patient received celecoxib capsules 200 mg orally twice daily, external application of n Pingying powder (平瘿散), and oral administration of traditional Chinese medicine decoction. The pain and mass disappeared after 21 days of treatments. One week later, similar symptoms occurred on the right side of the thyroid gland, the same dose of celecoxib capsules was given, but it was ineffective. So, it was replaced by prednisone acetate tablets 20 mg orally once daily. Twenty-five days later, the pain was relieved and the neck mass reduced. It was considered that the patient′s subacute thyroiditis was possibly due to quadrivalent lytic influenza virus vaccine.n