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恶性肿瘤和机体之间存在着复杂的矛盾关系,表现为肿瘤的侵袭性生长和宿主抵抗肿瘤生长两个方面。由于宿主反应体现了机体对肿瘤的抵抗,以及通过研究宿主反应在一定的程度上可能估计患者的予后,因而近年来颇受重视。肿瘤的间质反应则是宿主反应在形态学上的表现,因此,目前对肿瘤病理的研究已逐步从单纯描述肿瘤实质的形态进而重视间质变化的观察。本文以胃癌为研究对象,着重观察不同组织类型和不同生长方式胃瘤的间质反应,并初步与临床随访相结合,目的在于探讨间质反应与胃癌生长及予后的因果关系,以进一步认识其发生发展规律,为临床实践提供点滴基础理论资料。
There is a complex contradiction between malignant tumors and the body, manifested as invasive growth of the tumor and host resistance to tumor growth. Since the host response reflects the body’s resistance to tumors and the possibility of estimating the patient’s prognosis after studying the host response to a certain extent, it has received considerable attention in recent years. The mesenchymal response of tumors is the morphological manifestation of the host response. Therefore, the current research on tumor pathology has gradually focused on the observation of the changes in the morphology of tumors and the observation of interstitial changes. This article takes gastric cancer as the research object, focusing on observing the interstitial reactions of gastric tumors of different tissue types and different growth methods, and is initially combined with clinical follow-up. The purpose is to explore the relationship between the interstitial reaction and the growth and the causal relationship of gastric cancer in order to further understand The law of occurrence and development provides basic theoretical data for clinical practice.