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本文目的为观察延胡索浸剂对家兔、豚鼠及大白鼠等的离体小肠和家兔在体小肠的影响.并以X射綫观察延胡索浸剂口服常用剂量时,对正常人造影食通过胃肠道的影响.结果如下:(1)延胡索浸剂对豚鼠离体小肠产生兴奋作用,但对家兔及大白鼠离体小肠未产生显著作用.(2)于家兔、豚鼠及大白鼠离体小肠,延胡索浸剂可以拮抗乙酰胆碱、毛果芸香碱及氯化钡等所产生的肠张力上升作用.(3)延胡索浸剂于家兔耳静脉注入能引起在体小肠暂时性兴奋,此兴奋不被苯海拉明、六甲溴铵、阿讬品及两侧迷走神经切断等所阻断.(4)延胡索浸剂于相当10克生药的剂量时,对正常成人胃肠道活动无显著影响.
The purpose of this paper is to observe the effects of Corydalis Rhizoma on the intestinal tract of small intestine and rabbit in vitro, such as rabbits, guinea pigs and rats, and to observe the effects of Corydalis Succulent (1) Corydalis membranaceus had excitatory effect on isolated guinea pig small intestine, but had no significant effect on the isolated small intestine of rabbits and rats. (2) In rabbits, guinea pigs and rats Small intestine and Corydalis Rhizoma could antagonize the increase of intestinal tension induced by acetylcholine, pilocarpine and barium chloride. (3) The injection of Corydalis Rhizoma in rabbit ear vein can cause temporary excitability in the small intestine, which is not excited by benzene Hylegamine, hexamethonium bromide, aconite and vagotomy on both sides of blockage, etc. (4) Corydalis Rhizoma had no significant effect on the activity of gastrointestinal tract in normal adults when it was equivalent to 10g of crude drug.