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目的:观察金莲花胶囊联合康复新口服液治疗复发性口腔溃疡的临床疗效,及对患者生存质量的改善作用。方法:选取在本院接受治疗的180例复发性口腔溃疡患者为研究对象,按随机数字表法分为观察组和对照组各90例。对照组给予康复新口服液治疗,观察组在对照组用药基础上加用金莲花胶囊。比较2组总有效率、溃疡持续时间、疼痛指数以及治疗前后生存质量的变化。结果:治疗后,观察组总有效率为93.33%,高于对照组的75.26%(P<0.01);观察组的溃疡持续时间短于对照组(P<0.01),溃疡疼痛指数小于对照组(P<0.01)。治疗前,2组生理功能、社会功能、生理职能、躯体疼痛、精神健康、情感职能、活力、总体健康以及平均生活质量评分比较,差异均无统计学意义(P<0.05)。治疗后,2组以上9项评分均较治疗前上升(P<0.05);观察组以上9项评分均高于对照组(P<0.05)。结论:金莲花胶囊联合康复新口服液治疗复发性口腔溃疡,临床疗效优于单纯使用康复新口服液,可进一步缩短患者的溃疡持续时间,改善溃疡疼痛状况和生存质量。
Objective: To observe the clinical curative effect of the Golden Lotus Capsule combined with Kang Fu Xin Oral Liquid in the treatment of recurrent oral ulcer, and to improve the quality of life of patients. Methods: A total of 180 patients with recurrent oral ulcer treated in our hospital were enrolled in this study. The patients in observation group and control group were divided into two groups according to random number table. The control group was given Kang Fu Xin Oral Liquid, while the observation group was given the Golden Lotus Capsule on the basis of the control group. The total effective rate, ulcer duration, pain index and quality of life before and after treatment were compared between two groups. Results: After treatment, the total effective rate in the observation group was 93.33%, higher than that in the control group (75.26%, P <0.01). The duration of ulcer in the observation group was shorter than that in the control group (P <0.01) P <0.01). Before treatment, there were no significant differences in the scores of physical function, social function, physical function, physical pain, mental health, emotional function, vitality, general health and the average quality of life before treatment (P <0.05). After treatment, the scores of two groups of more than 9 increased compared with those before treatment (P <0.05). The above 9 scores of the observation group were higher than those of the control group (P <0.05). CONCLUSION: The combination of Jincan capsule and Kangfuxin oral liquid in the treatment of recurrent oral ulcer has better clinical curative effect than that of Kangfuxin oral liquid, which can further shorten the duration of ulcer and improve the ulcer pain status and quality of life.