2004年版WHO《肺、胸膜、胸腺和心脏肿瘤病理学和遗传学分类》中关于肺癌的部分增加了肺泡腔隙充填型周围型鳞状细胞癌(alveolar space-filling type of peripheral)的内容[1,2]。其特点为肿瘤细胞充填肺泡腔隙,没有破坏肺泡框架结构。由于研究尚少,在WHO分类中未做为一个独立 The 2004 edition of the WHO section on lung cancer in the Pulmonary, Pleural, Thymus, and Cardiac Oncology Pathology and Genetics category adds alveolar space-filling type of peripheral [1 ,2]. It is characterized by alveolar lavage filled with tumor cells without disrupting the alveolar frame structure. As the research is still small, not in the WHO classification as an independent