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用茶皂素对日本血吸虫中间宿主钉螺进行杀灭试验，初步结果表明：不同类型的茶皂素浸杀成螺、幼螺和螺卵均有较好的杀灭效果。其中茶皂素Ⅰ２．５ｍｇ／Ｌ，茶皂素Ⅱ、Ⅲ５．０ｍｇ／Ｌ，浸杀钉螺效果均为１００％。喷杀成螺所需浓度较高，效果也稍差。茶皂素对淡水鱼类虽有一定毒性，但比氯硝柳胺毒性低得多，茶皂素Ⅰ在１．６ｍｇ／Ｌ以下，茶皂素Ⅱ、Ⅲ在４．０ｍｇ／Ｌ以下，水温在２８℃，４８ｈ，鲢鱼全部存活。并且，药物资源丰富，价格低廉，对环境无污染，是一种具有开发前景的植物杀螺剂。文中还对不同类型茶皂素的毒性差异原因、施用浓度和方法进行了讨论。
Tea saponin was used to kill snails of Schistosoma japonicum. The preliminary results showed that different types of tea saponin had better killing effect. Which tea saponin Ⅰ 2.5mg / L, tea saponin Ⅱ, Ⅲ 5.0mg / L, dip snail snail effect is 100%. Spray kill into the required higher concentration, the effect is also slightly worse. Tea saponin has certain toxicity to freshwater fish, but it is much less toxic than niclosamide. Tea saponin I is below 1.6mg / L, tea saponin II and III are below 4.0mg / L, water temperature At 28 ℃, 48h, silver carp all survived. And, the drug is rich in resources, low prices, pollution-free environment, is a development of the plant with a narcotic agent. The paper also discusses the differences in the toxicity of different types of tea saponin, application concentration and method were discussed.