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甾体抗生育药物是生殖药物学的重要组成部分,20余年来,在人类控制生育方面发挥了十分重要的作用。最近10年间,这类药物的研究与开发取得了不少令人鼓舞的进展。目前有三种选择性更高的强效孕激素,即地索高诺酮、醋高诺酮肟和△~(15)—D—甲炔诺酮,已作为较好的新避孕药上市应用,据认为将会取代现用的炔诺酮和D—甲炔诺酮;Mifepristone和Epostane等则是新一代抗早孕药(Contragestive agent),临床前景引人
Steroidal anti-fertility drugs are an important part of reproductive medicine. For more than 20 years, steroid anti-fertility drugs have played a very important role in the control of reproduction. In the recent 10 years, there have been many encouraging developments in the research and development of such drugs. There are currently three more selective and more potent progestins, ie desopostin, acetophenone oxime and [Delta] -15-D-norethindrone, which have been marketed as better new birth control pills, It is believed that it will replace the existing norethindrone and D-norethindrone; Mifepristone and Epostane and so on is a new generation of anti-pregnancy drug (Contragestive agent), clinical prospects