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目的 探讨舰船环境对口腔幽门螺杆菌（Ｈ．ｐｙ１ｏｒｉ）孳生的作用和对消化性溃疡（ＰＵ）的影响。方法 对舰船患ＰＵ者６０例和非ＰＵ者６０例进行口腔卫生调查，同时对其使用的牙刷和口腔牙菌斑进行Ｈ．ｐｙｌｏｒｉ－ＰＣＲ检测，以６０名陆地人员作为对照。结果 口腔卫生ＰＵ组忧良率仅３８．３％，明显低于非ＰＵ组（７０．０％）和陆地组（７３．３％）（Ｐ＜０．０５）。Ｈ．ｐｙｌｏｒｉ－ＰＣＲ检测发现，牙刷Ｈ．ｐｙｌｏｒｉ阳性率舰船两组分别为５６．７％和４８．３％，明显高于陆地组３５．０％（Ｐ＜０．０５）；牙菌斑Ｈ．ｐｙｌｏｒｉ阳性率三组分别为８ｌ．７％，３１．７％和３６．７％，ＰＵ组明显比其他组高（Ｐ＜０．０１），非ＰＵ组与陆地组无显著性差异（Ｐ＞０．０５）。结论 舰船环境适于Ｈ．ｐｙｌｏｒｉ在牙刷上孳生，Ｈ．ｐｙｌｏｒｉ在口腔的聚集受口腔卫生的影响，ＰＵ的发病可能与口腔Ｈ．ｐｙｌｏｒｉ有关，舰船环境可能是船员ＰＵ发病率和复发率高的一个重要原因。
Objective To investigate the effect of warship environment on H. pylori (H. pylori) breeding and the effect on peptic ulcer (PU). Methods Oral hygiene was investigated in 60 patients with PU and non-PU in 60 ships, and the toothbrush and oral plaque used in the study were also performed. pylori-PCR test, with 60 land-based personnel as a control. Results The rate of oral hygiene in the PU group was only 38.3%, significantly lower than that in the non-PU group (70.0%) and the land group (73.3%) (P <0.05). H. The pylori-PCR test found that toothbrush H. The positive rates of pylori were 56.7% and 48.3% in the two groups, respectively, which were significantly higher than those in the land group (35.0%, P <0.05). The positive rate of pylori was 8l in each group. 7%, 31.7% and 36.7% respectively. The PU group was significantly higher than the other groups (P <0.01). There was no significant difference between the non-PU group and the land group (P> 0.05). Conclusion Ship environment suitable for H. Pylori breed on toothbrush, H. The accumulation of pylori in the oral cavity is affected by oral hygiene, and the incidence of PU may be related to the oral cavity H. pylori, the environment of the ship may be an important reason for the high morbidity and recurrence rate of crew members.