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1例69岁女性患者,因心律失常、阵发性室上性心动过速,HR166次/min,给予胺碘酮150mg静脉推注。30min后,患者出现窦性心动过缓,低血压。HR35次/min,BP81/50mmHg。立即安装临时起搏器,静脉补液,静脉注射多巴胺,1h后缓解。后因心动过速间断发作,再次给予胺碘酮注射液300mg加入5%葡萄糖注射液50ml,以0.6mg/min泵入。次日实验室检查:ALT1770U/L,AST1360U/L,TBil130.20μmol/L,DBil98.40μmol/L;PT17.3s,INR1.45。停用胺碘酮,给予对症、支持治疗。1周后症状好转。
A 69-year-old female patient was given intravenous bolus of amiodarone 150 mg due to arrhythmia, paroxysmal supraventricular tachycardia, HR 166 times / min. After 30min, patients with sinus bradycardia, hypotension. HR35 times / min, BP81 / 50mmHg. Immediately install a temporary pacemaker, intravenous rehydration, intravenous injection of dopamine, 1h after remission. After the intermittent episodes of tachycardia, once again given amiodarone 300mg injection of 5% glucose injection 50ml, pumped to 0.6mg / min. The next day laboratory tests: ALT1770U / L, AST1360U / L, TBil130.20μmol / L, DBil98.40μmol / L; PT17.3s, INR1.45. Amiodarone withdrawal, given symptomatic, supportive treatment. After 1 week the symptoms improved.