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目的:探讨杀胚化瘀中药组方联合西药在输卵管妊娠患者中的临床治疗效果。方法:选取2014年10月—2015年10月医院诊治的60例输卵管妊娠患者资料进行分析,采用随机对照方法将患者分为对照组和实验组,每组30例,对照组采用米非司酮联合甲氨蝶呤治疗,实验组在对照组治疗基础上联合杀胚化瘀中药组方,比较两组临床疗效。结果:实验组5例显效,24例好转,治疗率为93.75%,显著高于对照组(3例显效,19例好转,治疗率为85%)(P<0.05);两组患者治疗前血β-HCG水平差异不显著(P>0.05);实验组治疗后3 d、治疗后5 d、治疗后7 d血β-HCG水平,显著低于对照组(P<0.05);实验组宫内妊娠率,显著高于对照组(P<0.05);实验组重复异位妊娠率、继发不孕率,显著低于对照组(P<0.05);实验组2例发生药物不良反应,发生率为6.67%,显著低于对照组(9例发生药物不良反应,发生率为30.00%)(P<0.05)。结论:输卵管妊娠患者在米非司酮联合甲氨蝶呤治疗基础上联合杀胚化瘀中药组方治疗效果理想,能够提高临床疗效,改善患者妊娠后生育情况,值得推广应用。
Objective: To investigate the effect of killing embryo and removing blood stasis medicine combined with western medicine in tubal pregnancy patients. Methods: The data of 60 cases of tubal pregnancy diagnosed in our hospital from October 2014 to October 2015 were analyzed. The patients were divided into control group and experimental group with 30 cases in each group. The control group was treated with mifepristone Combined methotrexate treatment, the experimental group in the control group based on the combination of anti-embryonic and blood stasis of Chinese medicine prescription, the clinical efficacy of the two groups were compared. Results: In the experimental group, 5 cases were markedly improved and 24 cases improved. The treatment rate was 93.75%, which was significantly higher than that of the control group (3 cases markedly improved and 19 cases improved, the treatment rate was 85%) (P <0.05) (P> 0.05). The level of β-HCG in the experimental group was significantly lower than that in the control group on the 3rd day, 5 d after the treatment and 7 d after the treatment in the experimental group (P <0.05) Pregnancy rate was significantly higher than the control group (P <0.05); experimental group repeated ectopic pregnancy rate, secondary infertility rate was significantly lower than the control group (P <0.05); experimental group 2 patients with adverse drug reactions, the incidence (6.67%), which was significantly lower than that of the control group (9 patients had adverse drug reactions, the incidence was 30.00%) (P <0.05). Conclusion: Tubal pregnancy patients combined with mifepristone combined with methotrexate on the basis of the combination of anti-embryonic and blood stasis traditional Chinese medicine prescription treatment effect is ideal, can improve clinical efficacy and improve pregnancy after pregnancy, which is worth popularizing and applying.