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目的分析研究耐多药肺结核采用左氧氟沙星治疗的临床治疗效果。方法抽取2011年7月~2013年11月在吉林省吉林市结核病防治研究所收治的患有耐多药肺结核的患者140例,采用随机抽取模式,随机均分为2组(n=70)。对照组患者采取常规临床治疗模式,实验组在常规临床治疗的基础之上采取左氧氟沙星治疗,对2组患者在经过临床治疗以后的治疗效果进行对比分析。结果通过临床治疗6个月以后,实验组临床治疗效果显著优于对照组,2组间差异具有统计学意义(P<0.05);临床治疗12个月以后,实验组临床治疗效果显著优于对照组,2组间差异具有统计学意义(P<0.05);实验组患者满意度显著优于对照组,2组间差异具有统计学意义。结论对耐多药肺结核采用左氧氟沙星治疗,其临床治疗效果明显,不良反应少,具有安全有效性,使患者的健康生活质量起到至关重要的作用,具有临床推广价值。
Objective To analyze the clinical efficacy of levofloxacin in the treatment of multidrug-resistant pulmonary tuberculosis. Methods A total of 140 patients with MDR-TB in our hospital from July 2011 to November 2013 in Jilin Province were enrolled and divided into two groups randomly (n = 70) by random sampling. The patients in the control group were treated by conventional clinical therapy. The experimental group was treated with levofloxacin on the basis of routine clinical treatment, and the therapeutic effect of the two groups after clinical treatment was compared and analyzed. Results After clinical treatment for 6 months, the effect of clinical treatment in the experimental group was significantly better than that in the control group, with significant difference between the two groups (P <0.05). After 12 months of clinical treatment, the clinical effect of the experimental group was significantly better than that of the control group The difference between the two groups was statistically significant (P <0.05). The satisfaction of the patients in the experimental group was significantly better than that of the control group. The difference between the two groups was statistically significant. Conclusion Levofloxacin-resistant multidrug-resistant pulmonary tuberculosis (TB-TB) is effective in clinical treatment with obvious clinical effects and few adverse reactions. It is safe and effective and plays a crucial role in patients’ quality of life. It has clinical value of promotion.