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目的了解北京市海淀区成年人病毒性腹泻的流行现况。方法采集2012年6月-2013年5月北京市海淀区某医院肠道门诊282例腹泻患者粪便标本,用荧光PCR检测5种常见腹泻病毒。结果 119份(42.20%,119/282)粪便标本检出至少1种病毒。轮状病毒、诺如病毒、星状病毒和札如病毒检出率分别为9.22%,26.60%,5.32%和2.84%,未检出肠道腺病毒。混合感染共5例,以诺如病毒和札如病毒组合占首位(60.00%,3/5)。病毒性腹泻检出以20~40岁年龄组为主,流行高峰是秋冬季节。结论诺如病毒是2012-2013年北京市海淀区成年人病毒性腹泻最主要的病原体,其次是轮状病毒;混合感染占一定比例,在以后的流行病学及病原学研究中应该更加关注混合感染的出现。
Objective To understand the prevalence of adult viral diarrhea in Haidian District, Beijing. Methods Stool samples from 282 patients with diarrhea in a gut clinic of a hospital in Haidian District, Beijing from June 2012 to May 2013 were collected. Five common diarrhea viruses were detected by fluorescence PCR. Results 119 (42.20%, 119/282) stool specimens detected at least 1 virus. Rotavirus, Norovirus, Astrovirus and Sapporo virus detection rates were 9.22%, 26.60%, 5.32% and 2.84%, no detection of intestinal adenovirus. Mixed infection in 5 cases, the combination of Norovirus and Sapporo virus accounted for the first (60.00%, 3/5). Viral diarrhea was detected in 20 to 40 age group, the peak season is the autumn and winter. Conclusions Norovirus is the most important pathogen of adult viral diarrhea in Haidian District, Beijing from 2012 to 2013, followed by rotavirus. The mixed infection accounts for a certain proportion, and more attention should be paid to future mixed epidemiological and etiological studies The emergence of infection.