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目的:观察百令胶囊联合福莫特罗布地奈德对成人哮喘持续期患者免疫功能的影响。方法:将80例支气管哮喘持续期患者随机分为治疗组和对照组各40例。对照组给予吸入福莫特罗布地奈德,每次1吸(160ug/4.5ug),每日两次;治疗组另加用百令胶囊,每次5粒,每日3次,疗程12周;观察治疗前后两组临床疗效和免疫指标变化。结果:治疗组总有效率95%优于对照组总有效率85%,比较差异有统计学意义(P<0.05);治疗组TNF-a及IL-6水平较对照组明显降低。结论:百令胶囊联合福莫特罗布地奈德治疗持续期支气管哮喘患者,可有效缓解临床症状,提高免疫功能,减少急性发作。
Objective: To observe the effect of Bailing capsule and formoterol budesonide on the immune function in patients with persistent asthma. Methods: 80 patients with persistent bronchial asthma were randomly divided into treatment group and control group, 40 cases each. The control group was given inhalation of formoterol budesonide, each inhalation (160ug / 4.5ug) twice daily; treatment group plus another hundred capsules, each 5 times a day for 12 weeks The changes of clinical curative effect and immune index were observed before and after treatment. Results: The total effective rate in the treatment group was 95%, which was significantly higher than that in the control group (85%). The difference was statistically significant (P <0.05). The levels of TNF-a and IL-6 in the treatment group were significantly lower than those in the control group. Conclusion: Bailing capsule combined with formoterol budesonide in patients with persistent bronchial asthma can effectively relieve clinical symptoms, improve immune function and reduce acute attack.