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目的评估耳或颞骨恶性肿瘤侧颞骨切除术(LTBR)治疗的临床效果。方法回顾2000-2007年接受LTBR治疗的耳或颞骨恶性肿瘤患者病历。结果35例患者中,平均62.7岁,其中包括鳞状细胞癌(SCC)20例,基底细胞癌(BCC)7例,腺样囊性癌(ACC)7例,腺癌1例。5年生存率(OS)、疾病特异生存率(DSS)和无瘤生存率(DFS)分别为77%、79%和52%。完全切除能够改善OS、DSS和DFS(均P<0.004)并减少局部复发(P<0.001)。结论耳和颞骨恶性肿瘤患者中,上-前部切除包括LTBR结合术后放射的治疗有效。完全切除所有病灶能够改善生存率并减少复发。
Objective To evaluate the clinical effect of lateral temporoparietal resection (LTBR) treatment of otolatal or temporal bone tumors. Methods The medical records of patients with malignant tumors of the ear or temporal bone who underwent LTBR treatment during 2000-2007 were reviewed. Results Of the 35 patients, the average age was 62.7 years old, including 20 cases of squamous cell carcinoma (SCC), 7 cases of basal cell carcinoma (BCC), 7 cases of adenoid cystic carcinoma (ACC) and 1 case of adenocarcinoma. The 5-year OS, DSS, and DFS were 77%, 79% and 52%, respectively. Complete resection improved OS, DSS and DFS (both P <0.004) and reduced local recurrence (P <0.001). Conclusions Among patients with otic and temporal bone malignancies, anterior-anterior resection including LTBR in combination with postoperative radiation is effective. Complete resection of all lesions can improve survival and reduce recurrence.