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【目的】评价小剂量右美托咪定对脊柱外科手术患者苏醒期躁动的影响。【方法】本院择期实施脊柱后路内固定手术的患者40例，ASAⅠ～Ⅲ级，随机双盲分为试验组（D组）和对照组（C组），每组20例，两组入复苏室前均未使用右美托咪定。入复苏室后D组静脉内给予右美托咪定以0．25μg／（kg?10 min）的速度持续泵入；C组给予等速率的生理盐水。观察和记录手术结束后患者自主呼吸恢复时间（T1）、呼之睁眼时间（T2）及清醒拔管时间（T3）；记录各时点及拔管后1 min（T4）、10 min（T5）、30 min（T6）患者的平均动脉压、心率、Riker镇静躁动评分。比较两组患者苏醒期的躁动情况以及血流动力学的变化。【结果】两组患者麻醉时间、手术时间、术后拔管时间和停留复苏室时间相比较差异无显著性（ P ＞0．05）；D组患者术后各时点的平均动脉压、心率，明显低于C组，且两组相比较差异有显著性（ P ＜0．05）；D组的术后躁动评分和躁动发生率低于C组，且两组相比较差异有显著性（ P ＜0．05）。【结论】脊柱外科手术后，应用右美托咪定可以减少患者手术后苏醒期躁动。“,”Objective] To explore the effects of small‐dose dexmedetomidine on the recovery of patients under‐going vertebral operations .[Methods]A total of 40 patients undergoing vertebral operations with American Society of Anesthesiologists (ASA) gradesⅠ~ Ⅲ were randomly divided into groups C and D ( n = 20 each) .In group D , dexmedetomidine was infused at a rate of 0 .25 μg/(kg?10 min) while group C received 0 .9% saline at the same rate .The mean arterial pressure ,heart rate and Riker sedation‐agitation scale were recorded at the timepoints of au‐tonomous respiration (T1 ) ,eye opening (T2 ) ,extubation (T3 ) ,1 min post‐extubation (T4 ) ,10 min post‐extuba‐tion (T5 ) and 30 min post‐extubation (T6) .And restlessness and hemodynamic changes were compared .[Results]No significant difference existed in time of anesthesia ,time of operation ,time of extubation and time stayed in postan‐esthesia care unit (PACU) and scores for emergence agitation pre‐anesthesia ( P > 0 .05) .There were significant difference in scores of emergence agitation after entry into PACU in group D versus group C ( P<0 .05) .The rate of emergence agitation was significantly lower in group D than that in group C ( P<0 .05) .[Conclusion] An infusion of dexmedetomidine provides satisfactory intraoperative conditions for vertebral operations .And the incidence and du‐ration of emergence agitation are lowered with dexmedetomidine .