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目的 :评价静脉滴注硝酸甘油 (NTG)介入 99m Tc-甲氧基异丁基异腈 (MIBI)心肌断层显像在心肌存活的估测价值。方法:对 44例心肌梗死患者先行常规静息态 99m Tc- MIBI心肌断层显像 ,2 4～ 48h后静脉滴注 NTG再行静息态心肌断层显像。 结果:静息态心肌断层显像检出异常灌注节段 2 2 9个。 NTG介入后有 5 9个节段恢复正常 ,44个节段明显改善 ,12 6个节段部分改善 ,NTG介入后的缺血 /正常 (I/ N )比值为 0 .70 9± 0 .136 ,明显较静息时的 (0 .6 49± 0 .12 4)增大。 结论:静脉滴注 NTG对提高静态 99m Tc- MIBI心肌断层显像估测心肌存活有一定的临床价值 ,这对冠心病血运重建术对象选择以及心肌梗塞患者的预后评价有重要作用。
OBJECTIVE: To evaluate the value of intravenous NTG in myocardial 99m Tc-methoxyisobutylisonitrile (MIBI) myocardial perfusion imaging. Methods: Forty-four patients with myocardial infarction were subjected to routine resting 99m Tc-MIBI myocardial perfusion imaging and NTG reconstructed with resting myocardial perfusion imaging 24-48 h later. Results: Resting myocardial perfusion imaging detected 229 abnormal perfusion segments. After NTG intervention, 59 segments returned to normal, 44 segments improved significantly, 12 6 segments improved partially, and the ratio of ischemia / normality (I / N) after NTG intervention was 0.70 9 ± 0.136 , Significantly (0.669 ± 0.12 4) increased at rest. Conclusion: Intravenous instillation of NTG has some clinical value in improving the myocardial viability of 99m Tc-MIBI myocardial perfusion tomography, which plays an important role in the selection of subjects for coronary revascularization and the prognosis of patients with myocardial infarction.