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醋酸三烷基锗及β-羧乙基锗倍半氧化物(Ge-132)有抑菌及抗癌作用。Ge-132的某些衍生物具有更强的抗癌活性。本文报道8种酰胺衍生物的合成,它们的光谱、质谱及热分解性质和部分衍生物的抗癌活性。
Trialkyl germanium acetate and β-carboxyethyl germanium sesquioxide (Ge-132) has antibacterial and anti-cancer effects. Certain derivatives of Ge-132 have stronger anticancer activity. This paper reports the synthesis of eight amide derivatives, their spectral, mass and thermal decomposition properties and the antitumor activity of some derivatives.