The correlation of flare's location on solar disc with the value of sudden increase of total electron content is analyzed with flare's parameters observed by GOES satellite from 1997 to 1999 and total electron content derived from GPS data observed by international GPS Service for Geodynamics. It is found that, besides the flare's maximum X-ray flux, flare's location on solar disc has some relation with the value of SITEC during the flare. The ionospheric response to a flare with a smaller maximum X-ray flux and nearer angular distance to the Sun's central meridian line may be stronger than that of the flare with a larger maximum X-ray flux and far angular distance. To the flares with the same class of maximum X-ray flux, the nearer the angular distance to the Sun's meridian, the stronger the ionospheric response.