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  5. Alteration of oncogenic IGF-Ⅱ gene methylation status associates with hepatocyte malignant transform

Alteration of oncogenic IGF-Ⅱ gene methylation status associates with hepatocyte malignant transform

来源 :国际肝胆胰疾病杂志:英文版 | 被引量 : 0次 | 上传用户：smilepk
【摘 要】
：
Background:Oncogenic insulin-like growth factor-Ⅱ(IGF-Ⅱ)is overexpressed in hepatocellular carcinoma(HCC).The present study aimed to analyze the dynamic alter
【作 者】
：
Bo-Jun Tai Min Yao Wen-Jie Zhe 
【机 构】
：
DepartmentofInfectiousDiseases,DepartmentofImmunology,DepartmentofOncology,DepartmentofOncology
【出 处】
：
国际肝胆胰疾病杂志:英文版
【发表日期】
：
2019年2期
【关键词】
：
Hepatocellular carcinoma INSULIN-LIKE growth factor-Ⅱ HYPOMETHYLATION Methylatio 
【基金项目】
：
grants from the National Natural Science Foundation(81673241,81702419,81872738,81873915),the Jiangsu Medical Science(BE2016698)&Graduate Innovation(KYCX17_1934),the International S.&T.Cooperat
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Background:Oncogenic insulin-like growth factor-Ⅱ(IGF-Ⅱ)is overexpressed in hepatocellular carcinoma(HCC).The present study aimed to analyze the dynamic alteration of IGF-ⅡCpG site methylation status and its molecular mechanism in HCC progression.Methods:
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