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目的探讨小牛血清去蛋白注射液(奥德金)在流行性乙型脑炎中的临床应用。方法77例流行性乙型脑炎患儿,随机分成治疗组(40例)和对照组(37例),治疗组在常规综合治疗基础上加用小牛血清去蛋白注射液,对照组采用常规综合治疗。结果治疗组总有效率97.5%,对照组总有效率81.1%,治疗组的疗效明显优于对照组(P<0.05),治疗组退热时间、神志清醒时间及住院时间均明显小于对照组(P<0.01)。无明显不良反应。结论小牛血清去蛋白注射液治疗流行性乙型脑炎疗效较好且安全,值得临床推广。
Objective To investigate the clinical application of deproteinization of calf serum (Odegin) in Japanese encephalitis. Methods Totally 77 children with epidemic encephalitis were randomly divided into treatment group (n = 40) and control group (n = 37). The treatment group was treated with bovine serum deproteinized injection on the basis of conventional comprehensive treatment. The control group was treated with routine Comprehensive Treatment. Results The total effective rate was 97.5% in the treatment group and 81.1% in the control group. The curative effect of the treatment group was significantly better than that of the control group (P <0.05). The antipyretic time, conscious time and hospital stay in the treatment group were significantly less than those in the control group P <0.01). No obvious adverse reactions. Conclusions Bovine serum deproteinized injection is effective and safe for the treatment of Japanese encephalitis, which is worthy of clinical promotion.