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目的探讨醒脑静联合高压氧治疗一氧化碳中毒迟发性脑病的临床疗效。方法选取2010年3月至2014年11月虞城县人民医院收治的59例一氧化碳中毒并发迟发性脑病患者,随机分为观察组(31例)和对照组(28例),对照组在常规治疗的基础上加用醒脑静治疗,观察组在对照组治疗的基础上联合高压氧治疗,对比两组患者的治疗效果及苏醒时间。结果观察组患者苏醒时间为(3.15±1.25)h,显著高于对照组的(5.24±1.35)h,两组比较差异有统计学意义(P<0.05);观察组患者经治疗后临床总有效率为93.55%,显著高于对照组的78.57%,经统计学分析,差异具有统计学意义(P<0.05)。结论醒脑静药物联合应用高压氧治疗一氧化碳中毒迟发性脑病后,能有效提高患者的治疗效果,且能大大缩短患者苏醒时间,提高恢复速率。
Objective To investigate the clinical effects of xingnaojing combined with hyperbaric oxygen on delayed encephalopathy caused by carbon monoxide poisoning. Methods 59 patients with carbon monoxide poisoning complicated with delayed encephalopathy who were admitted to Yucheng County People’s Hospital from March 2010 to November 2014 were randomly divided into observation group (31 cases) and control group (28 cases), while those in control group On the basis of treatment, xingnaojing was added. The observation group was treated with hyperbaric oxygen on the basis of the control group, and the treatment effect and recovery time were compared between the two groups. Results The recovery time of the observation group was (3.15 ± 1.25) h, which was significantly higher than that of the control group (5.24 ± 1.35) h, with significant difference between the two groups (P <0.05). In the observation group, The efficiency was 93.55%, which was significantly higher than 78.57% of the control group. The difference was statistically significant (P <0.05). Conclusion Xingnaojing combined with hyperbaric oxygen treatment of delayed encephalopathy after carbon monoxide poisoning can effectively improve the therapeutic effect of patients, and can greatly shorten the recovery time of patients and improve the recovery rate.