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目的比较分析矮小症与正常身高儿童健康相关生活质量的差异。方法选取2015年10月至2016年4月就诊于济宁医学院附属医院生长发育门诊且符合入选标准的494例5~18岁儿童及其主要监护人为研究对象。将494例分为矮小症组、身高偏矮组、正常身高组,采用Peds QL4.0核心通用量表进行横断面研究。结果 (1)Peds QL4.0核心通用家长代评量表中,矮小症组、身高偏矮组、正常身高组总分分别为77.69±12.46,82.63±12.20,89.01±10.24(P<0.001);儿童自评量表中,总分分别为74.20±11.94,80.43±11.38,88.21±8.45(P<0.001)。(2)校正混杂因素后,矮小症组在Peds QL4.0核心通用自评与代评量表总分及各维度的评分仍最低,身高偏矮组次之,正常身高组最高(P<0.05)。(3)40例GHD患儿与21例ISS患儿相比,自评与代评量表在总分及各维度的评分差异无统计学意义(P>0.05)。结论身材矮小对儿童健康相关生活质量有负面影响。
Objective To compare and analyze the differences of health-related quality of life between short stature and normal height children. Methods From October 2015 to April 2016, 494 children aged 5 to 18 years and their main guardians who visited the growth and development clinics of Jining Medical College Affiliated Hospital and met the inclusion criteria were selected as the study objects. A total of 494 cases were divided into short stature group, short stature group, normal height group, using the Peds QL4.0 core universal scale for cross-sectional study. Results (1) The total score of Peds QL4.0 core universal parents scale was 77.69 ± 12.46,82.63 ± 12.20,89.01 ± 10.24 (P <0.001) in short stature group, short stature group and normal height group, respectively. Children’s self-rating scale, the total score was 74.20 ± 11.94,80.43 ± 11.38,88.21 ± 8.45 (P <0.001). (2) After the confounding factors were corrected, the short stature group had the lowest scores in the Peds QL4.0 core general self-assessment and scale and the scores in all dimensions, followed by the short stature group and the normal height group (P <0.05 ). (3) Compared with 21 ISS children, there were no significant differences in the scores of the total score and each dimension between the 40 children with GHD and the children with ISS (P> 0.05). Conclusion Short stature has a negative impact on children’s health-related quality of life.