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目的:对大剂量奥美拉唑治疗消化性溃疡合并消化道出血的临床疗效展开总结与探讨。方法:选取我院于2011年1月-2013年1月间收治的100例患有消化性溃疡合并消化道出血的患者资料,按照提供奥美拉唑用药剂量的不同,将资料分为对照组与实验组(各50例),前者给予常规剂量治疗,后者提供大剂量治疗。经相同周期,对于两组患者治疗有效性、溃疡愈合情况及止血时间进行统计与对比。结果:与对照组相比,实验组患者临床治疗有效性较高(对照组74%,实验组92%),患者溃疡愈合率显著提升(对照组72%,实验组94%),且止血时间缩短[对照组(27.5±9.5)h、实验组(21.0±6.0)h]。结论:大剂量奥美拉唑在消化性溃疡合并消化道出血临床治疗方面效果较理想,有利于缩短治疗周期,缓解溃疡、促进止血,值得临床推广应用。
Objective: To summarize and discuss the clinical efficacy of high-dose omeprazole in the treatment of peptic ulcer complicated with gastrointestinal bleeding. Methods: The data of 100 patients with peptic ulcer complicated with gastrointestinal bleeding admitted in our hospital from January 2011 to January 2013 were selected. The data were divided into control group And experimental group (50 cases each), the former is given conventional dose treatment, which provides high-dose treatment. After the same period, for the two groups of patients treatment effectiveness, ulcer healing and bleeding time statistics and comparison. Results: Compared with the control group, the clinical efficacy of the experimental group was higher (74% in the control group and 92% in the experimental group), and the healing rate of the ulcer in the experimental group was significantly improved (72% in the control group and 94% in the experimental group) Shortening [control group (27.5 ± 9.5) h, experimental group (21.0 ± 6.0) h]. Conclusion: The high-dose omeprazole is effective in the clinical treatment of peptic ulcer with gastrointestinal bleeding, which is beneficial to shorten the treatment cycle, relieve ulcer and promote hemostasis, and is worthy of clinical application.