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姜黄素是从姜科姜黄素属植物中提取的一种多酚类化合物,具有抗肿瘤、抗炎、抗氧化等作用,姜黄素能够在多方面起到抗肿瘤作用,而且不良反应小。姜黄素诱导肿瘤细胞凋亡,是其发挥抗肿瘤作用的重要机制之一。本文主要针对姜黄素诱导肿瘤细胞凋亡的作用靶点、作用途径及分子机制的研究进展作一综述。
Curcumin is a polyphenolic compound extracted from curcumin of Zingiberaceae. It has anti-tumor, anti-inflammatory and anti-oxidation effects. Curcumin can exert anti-tumor effect in many aspects and has a small adverse reaction. Curcumin induces tumor cell apoptosis, which is one of the important mechanisms of its anti-tumor effect. This review focuses on the role of curcumin in inducing tumor cell apoptosis and its possible mechanisms.