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目的:探讨中期妊娠引产方法的安全性和有效性。方法:回顾性分析山东菏泽牡丹人民医院一分院2012年6月~2013年6月疤痕子宫中期妊娠要求终止妊娠的孕妇100例,分为2组,其中A组为米非司酮+依沙吖啶(利凡诺)羊膜腔内注射引产方法;B组为米依沙吖啶(利凡诺)羊膜腔内注射引产方法。观察宫缩发动时间、分娩结局、用药至分娩时间、软产道裂伤、出血量、子宫破裂的发生情况。结果:2组的清宫率、引产成功率、子宫破裂及软产道裂伤的情况对比,差异无统计学意义(P>0.05);A组宫缩发动时间、用药至宫缩规律时间、用药至分娩时间短于B组,胎盘滞留率及胎膜残留率低于B组,2组比较差异具有统计学意义(P<0.05)。结论:对于疤痕子宫中期妊娠,两种方法均相对安全、有效。应用米非司酮配伍利凡诺羊膜腔内注射对中妊引产,应作为首选方法。能大大缩短引产时间,减少患者痛苦,降低住院费用,成功率高,值得推广应用。
Objective: To investigate the safety and efficacy of induction of labor in mid-term pregnancy. METHODS: A retrospective analysis of 100 cases of pregnant women who were required to terminate pregnancy during the second trimester of uterine scar pregnancy from June 2012 to June 2013 in Heze Peony People’s Hospital of Shandong Province was divided into two groups, in which group A was mifepristone + (Rivanol) intrahepatic amniotic injection induced abortion method; group B mieza acridine (rivanol) intrahepatic amniotic injection induced abortion method. Observation of contractions start time, delivery outcome, medication to delivery time, soft birth canal laceration, bleeding, the incidence of uterine rupture. Results: There was no significant difference between the two groups in the rate of uterine bleeding, the success rate of induction of labor, uterine rupture and laceration of soft birth canal (P> 0.05). The duration of uterine contractions in group A, The delivery time was shorter than that in group B, the retention rate of the placenta and the residual rate of fetal membranes were lower than those in group B, the difference was statistically significant (P <0.05). Conclusions: Both methods are relatively safe and effective for mid-term pregnancy with scarring. Application of mifepristone Rivaroxone intra-amniotic injection of mid-pregnancy induced abortion, should be the preferred method. Can greatly shorten the time of induction of labor, reduce patient suffering, reduce hospital costs, the success rate is high, it is worth promoting application.