一、二度冻伤及冻疮是部队战士的寒季多发病,也是劳动人民的多发病。部队中传统使用的“冻伤膏”,以及民间流传的许多治疗冻伤的“单方”和“复方”,其疗效均不够理想。为了使广大战士及寒区劳动人民的一、二度冻伤及冻疮得到快速治愈,从而保证部队战斗力和劳动力。我们进行了一、二度冻伤治疗药物的研究,通过临床调查及动物实验,对二度冻伤发病原理作初步分析并以此为重要依据,进行药物筛选工作。同时,对民间流传的验方,也进行筛选。共进行近千匹家兔实验,筛选了近百个方剂,发现以地塞米松或氢化可的松为主药的霜剂对二度冻伤实验疗效优异。经部队及地方广泛试用,效果良好,被命名为“冻伤膏一号”(“691”)。 First and second degree frostbite and frostbite are frequent illnesses in the cold season of army fighters, and are also frequent illnesses of working people. The “frozen wound cream” traditionally used in the army and the many “unilateral” and “compound” medicines circulating in the public to treat frostbite are not satisfactory. In order to make the majority of fighters and working people in the cold regions have a quick cure for frostbite and frostbite, thus ensuring the combat effectiveness and labor force of the troops. We carried out research on the first and second frostbite treatment drugs. Through clinical investigation and animal experiments, we conducted a preliminary analysis of the principle of secondary frostbite and used it as an important basis for drug screening. At the same time, the folklore prescriptions are also screened. A total of nearly 1,000 rabbit experiments were conducted, and nearly 100 prescriptions were screened. Creams containing dexamethasone or hydrocortisone as the main drug were found to have excellent curative effects on secondary frostbite. After a wide range of trials by the troops and localities, the results were good and they were named “Cold Frostbite No. 1” (“691”).