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丙型肝炎病毒(HCV)是致非甲非乙型肝炎的主要病原体,丙型肝炎患者血清中抗-HCV抗体水平与体内HCV数量有很好的正相关性,是病毒感染的一个标志。为了探讨HCV对慢性乙型肝炎患者肝脏的损害作用,作者用ELISA方法,对184名HBsAg阳性的肝炎病人进行了抗-HCA抗体检测。这些病人均有谷丙转氨酶的异常及慢性肝炎的组织学诊断依据。其中包括28位同时有HDV感染的病人。对照组为30名HBsAg阳性的“健康”携带者。
Hepatitis C virus (HCV) is the major causative agent of non-A, non-B hepatitis. The level of anti-HCV antibodies in serum of patients with hepatitis C is positively correlated with the number of HCV in vivo and is a sign of viral infection. In order to investigate the effect of HCV on liver damage in patients with chronic hepatitis B, the authors tested the anti-HCA antibody in 184 HBsAg-positive hepatitis patients by ELISA. These patients have alanine aminotransferase abnormalities and histological diagnosis of chronic hepatitis basis. This included 28 patients with HDV infection at the same time. The control group was 30 HBsAg-positive “healthy” carriers.