论文部分内容阅读
目的:通过比较患妊娠期高血压疾病妇女和非妊娠期高血压疾病妇女远期原发性高血压的发病率及血压水平,探讨可能影响妊娠期高血压疾病妇女远期血压水平的因素。方法:采用回顾性分析,收集2006年4月~2010年7月在该院住院并分娩的妇女396例,根据是否患妊娠期高血压疾病将入选对象分为妊娠期高血压疾病组42例,非妊娠期高血压疾病妇女354例设为对照组。入选对象的随访采用问卷形式,并抽取患者血液进行分析。结果:396例患者原发性高血压累积发病率为15.91%,其中娠期高血压疾病组为28.57%,对照组为14.41%,差异有统计学意义(χ2=5.631,P<0.05);妊娠期高血压疾病组的TC、GLU均高于对照组,差异有统计学意义(t=2.202、1.993,P<0.05);两组的白细胞计数、TG、LDL和UA值比较,差异均无统计学意义(P>0.05);妊娠期高血压疾病组收缩压、舒张压和脉压差均高于对照组,差异有统计学意义(t=-13.599、-12.092、-5.627,P<0.05);两组的年龄、孕周、高血压家族史比较差异均无统计学意义。结论:娠期高血压疾病妇女远期原发性高血压累积发病率高于非妊娠期高血压疾病者;血糖和胆固醇水平升高可能是导致妊娠期高血压疾病患者远期血压水平升高的因素。
Objective: To compare the long-term incidence of essential hypertension and blood pressure in women with gestational hypertension and non-pregnancy-induced hypertension in order to explore the factors that may affect the long-term blood pressure of women with gestational hypertension. Methods: A retrospective analysis was performed to collect 396 women hospitalized and delivered in this hospital from April 2006 to July 2010. According to whether or not they had hypertensive disorder complicating pregnancy, the subjects were divided into 42 cases of hypertensive disorder complicating pregnancy, 354 women with non-pregnancy-induced hypertension were enrolled as control group. Participants were followed up by questionnaire, and the patient’s blood was drawn for analysis. Results: The cumulative incidence of essential hypertension in 396 patients was 15.91%, which was 28.57% in hypertensive disorder in pregnancy and 14.41% in control group (χ2 = 5.631, P <0.05). Pregnancy The levels of TC and GLU in hypertension group were higher than those in control group (t = 2.202, 1.993, P <0.05). There were no statistic differences in TC, GLU, TG, LDL and UA between the two groups (P> 0.05). The systolic blood pressure, diastolic blood pressure and pulse pressure difference in hypertensive disorder complicating pregnancy were significantly higher than those in control group (t = -13.599, -12.092, -5.627, P <0.05) There was no significant difference between the two groups in age, gestational age and family history of hypertension. Conclusions: The cumulative incidence of long-term hypertension in patients with hypertensive disorders in pregnancy is higher than that in non-pregnant hypertensive patients. Elevated blood glucose and cholesterol may be the cause of elevated blood pressure in patients with hypertensive disorder complicating pregnancy factor.