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Avermectins是一类新型的高效广谱的抗生素类农药，对多种害虫及害螨具有极好的防效。本文简要综述了家蝇、马铃薯甲虫、二斑叶螨等对avermectins的抗药性发展状况及其抗性机制。研究表明，家蝇对avermectins的抗性主要与表皮穿透性降低有关，马铃薯甲虫对avermectins的抗性主要与多功能氧化酶的活性增强有关，二斑叶螨对avermectins的抗性与其对药剂的排泄能力、代谢能力以及轭合作用增强有关。文章还讨论了avermectins抗药性的治理策略。
Avermectins is a new class of highly efficient, broad-spectrum antibiotic-based pesticide that provides excellent control over a wide range of pests and pests. This article briefly reviewed the development of resistance to avermectins, such as housefly, potato beetle and two-spotted spider mites, and their resistance mechanisms. Studies have shown that the resistance of houseflies to avermectins is mainly related to the decrease of epidermal penetration. The resistance of potato beetle to avermectins is mainly related to the enhancement of the activity of multifunctional oxidase. The resistance of two-spotted spider mite to avermectins and its resistance to avermectins Excretion, metabolism and increased conjugation. The article also discusses strategies for managing avermectins resistance.