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目的探讨中青年急性心肌梗死(AMI)临床特点。方法分析中青年组(年龄<60岁,143例)和老年组(年龄≥60岁,274例)AMI患者的既往疾病、实验室检查和冠状动脉(冠脉)造影资料以及主要不良心血管事件(MACE)的发生情况。结果与老年组相比,中青年组患者中的男性和有吸烟史的比例较高,有高血压及梗死前心绞痛病史比例、WBC计数、血尿酸和额面QRS-T夹角值均较低(P<0.05)。中青年组侧支循环形成者的比例低于老年组(7.7%vs.15.0%)(P<0.05),冠脉Gensini积分在3~38分者的比例高于老年组(48.3%vs.35.4%)(P<0.05)。中青年组MACE发生率低于老年组(12.6%vs.23.7%)(P<0.05)。结论中青年AMI好发于男性和吸烟人群。根据实验室检查、额面QRS-T夹角值和冠脉Gensini积分,可以初步评估AMI患者病情。
Objective To investigate the clinical features of middle-aged and young patients with acute myocardial infarction (AMI). Methods Prevalence, laboratory and coronary (angiographic) coronary angiography data, and major adverse cardiovascular events in AMI patients aged <60 years, 143 patients and elderly patients (≥60 years, 274 patients) (MACE) of the situation. Results Compared with the elderly group, there was a higher prevalence of smoking among men and smokers in the middle-aged and younger age groups. There was a history of hypertension and the history of pre-infarction angina, and WBC count, serum creatinine and frontal QRS-T included values were lower (P <0.05). The proportion of collateral circulation in young group was lower than that of the elderly group (7.7% vs.15.0%) (P <0.05), and the proportion of coronary artery with Gensini score of 3-38 was higher than that of the elderly group (48.3% vs.35.4 %) (P <0.05). The incidence of MACE in young and middle ages group was lower than that in the elderly group (12.6% vs.23.7%) (P <0.05). Conclusions The young and middle aged AMI occur in male and smokers. According to laboratory tests, frontal QRS-T angle and coronary Gensini integral, AMI patients can be a preliminary assessment of the disease.