人参果提取物体内具显著降血糖和减肥活性,其主要成分人参皂苷 Re 在Ⅱ型糖尿病鼠模型中具显著的抗高血糖活性。作者分析了具有 obese 基因(肥胖基因)突变基因 ob/ob 的 C57BL/6J 小鼠的胰岛素敏感性和葡萄糖内环境。ob/ob 基因可导致极度肥胖和胰岛素耐药性。小鼠每日腹腔注射人参果提取物50mg/kg 或150mg/kg,共12天。在另一研究中,小鼠腹腔注射人参皂 Ginseng fruit extract has significant hypoglycemic and anti-obesity activity. Its main component, ginsenoside Re, has a significant anti-hyperglycemia activity in type II diabetic murine model. The authors analyzed insulin sensitivity and glucose homeostasis in C57BL/6J mice with the obese gene ob/ob. The ob/ob gene can cause extreme obesity and insulin resistance. The mice were injected intraperitoneally with 50 mg/kg or 150 mg/kg of ginseng fruit extract for 12 days. In another study, mice were injected intraperitoneally with ginsenosides