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目的探讨艾滋病患者抗病毒治疗服药依从性及影响因素。方法采用分层随机抽样的方法,对河南省5个艾滋病防治示范县/市的796名抗病毒治疗患者进行调查,并对相关影响因素进行Logistic回归分析。结果调查结果显示,有704(88.4%)人服药依从性好;单因素分析显示,不同收入水平(χ2=7.674,P=0.022)、确诊年限(χ2=5.203,P=0.023)、社会支持程度(t=2.870,P=0.004;t=2.500,P=0.013;t=2.337,P=0.020)等对患者服药依从性的影响具有统计学意义;Logistic回归分析显示,影响患者服药依从性的主要因素是:确诊年限(P=0.006,OR=0.401)、收入水平(P=0.003,OR=0.364)、客观支持(P<0.001,OR=1.180)、主观支持(P=0.002,OR=1.075)、支持的利用度(P=0.005,OR=1.163)。结论河南省艾滋病患者服药依从性仍需进一步提高,在今后的抗病毒治疗中,应进一步提高患者的社会支持水平以提高其服药依从性。
Objective To investigate the adherence and influencing factors of anti-virus therapy in patients with AIDS. Methods A stratified random sampling method was used to investigate 796 ARV patients in 5 HIV / AIDS prevention / treatment counties / cities in Henan Province. Logistic regression analysis was performed on the related factors. The results of the survey showed that 704 (88.4%) had good medication compliance. Univariate analysis showed that the level of social support (χ2 = 5.203, P = 0.023) (t = 2.870, P = 0.004; t = 2.500, P = 0.013; t = 2.337, P = 0.020) had statistical significance on the compliance of patients. Logistic regression analysis showed that the main influential factors (P = 0.002, OR = 0.404), objective support (P <0.001, OR = 1.180), subjective support (P = 0.002, OR = 1.075) , Supported utilization (P = 0.005, OR = 1.163). Conclusion HIV compliance in Henan Province still needs to be further improved. In the future antiviral treatment, the level of social support should be further improved to improve compliance.