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多胺(腐胺、精脒、精胺)是真核细胞体内重要的多聚阳离子,对细胞的生长增殖发挥重要作用。快速生长的细胞内含有高浓度的多胺,降低多胺含量将抑制细胞的生长,阻滞细胞周期,而升高多胺含量则会促进细胞快速生长增殖。对多胺的调控已经成为研究细胞生长增殖调控的切入点之一。
Polyamines (putrescine, spermidine, spermine) are important polycations in eukaryotes and play an important role in the growth and proliferation of cells. Rapidly growing cells contain high concentrations of polyamines, reducing polyamine content will inhibit cell growth, arresting cell cycle, while increasing the content of polyamines will promote rapid cell growth and proliferation. The regulation of polyamines has become one of the starting points to study the regulation of cell growth and proliferation.