病例报告 例1 男,19岁。于12岁开始每遇寒冷或足趾蹠屈时出现双足屈曲性痉挛。近年来痉挛加重。半年来全身多汗,并觉两下肢乏力。近1个月出现小腿、臀部及肩臂部肌肉跳动,双手指和足趾遇冷时发生痉挛与疼痛,且手足发冷,心悸,多汗,食欲减退和体重下降。无家族病史。体检:四肢末梢性感觉减退, Case report 1 male, 19 years old. At 12 years of age, there was a bi-flexion cramp in each cold or toe plantar flexion. Spasticity in recent years increased. Six months sweating, and feel both lower extremity fatigue. In the past month, the muscles of the lower legs, buttocks and shoulders were beating. His hands and feet met with spasms and pain when they were cold, and had chills, palpitations, sweating, loss of appetite and weight loss. No history of family history. Physical examination: peripheral sensory weakness,