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目的探讨厦门市居民肝癌死亡变化趋势,为厦门市肝癌综合防治工作提供依据。方法通过厦门市死因监测系统收集2005-2014年厦门市居民肝癌死亡资料,计算死亡率、标化死亡率(以2010年全国人口普查数据为标准人口)、死亡年龄中位数和四分位数(P25~P75)等评价指标。用SAS 9.2软件进行多因素logistic回归分析,分析肝癌死亡的影响因素。结果 2005-2014年,厦门市居民肝癌死亡率为31.35/10万,标化死亡率33.30/10万,死亡率年均下降1.65%;男性死亡率(49.84/10万)是女性(12.76/10万)的3.90倍,男性标化死亡率(54.75/10万)是女性(12.93/10万)的4.23倍。死亡率随着年龄的增长逐渐升高,死亡年龄中位数为57岁(P25~P75:48~69岁)。多因素logistic回归分析结果表明,男性(OR=4.42,95%CI:4.14~4.72)、年龄越大(OR=1.33,95%CI:1.33~1.34)、生活在农村(OR=1.49,95%CI:1.41~1.57)和2005-2009年时间段(OR=1.08,95%CI:1.02~1.14)可能是肝癌死亡的危险因素。结论厦门市居民肝癌死亡率仍保持较高态势,不能放松警惕,应以农村、男性、老年人群作为重点关注对象,加强肝癌防治工作。
Objective To explore the trend of mortality of liver cancer in Xiamen residents and provide basis for comprehensive prevention and treatment of liver cancer in Xiamen City. Methods The mortality data of Xiamen residents from 2005 to 2014 were collected from the cause of death monitoring system of Xiamen City from 2005 to 2014 to calculate the mortality rate and the standardized mortality rate (with the 2010 national census data as the standard population), the median age at death and quartiles (P25 ~ P75) and other evaluation indicators. Multivariate logistic regression analysis with SAS 9.2 software was used to analyze the influencing factors of liver cancer death. Results In 2005-2014, the mortality rate of liver cancer in Xiamen was 31.35 / lakh and the standardized mortality rate was 33.30 / lakh. The mortality rate dropped by 1.65% annually. The male mortality rate (49.84 / lakh) was female (12.76 / 10 3.90 times as many as males, and the male standardized mortality rate (54.75 / 100,000) was 4.23 times that of females (12.93 / 100,000). Mortality increased with age and median age at death was 57 years (P25-P75: 48-69). Multivariate logistic regression analysis showed that in men (OR = 4.42, 95% CI: 4.14-4.72), the older the age was (OR = 1.33, 95% CI: 1.33-1.34) CI: 1.41-1.57) and 2005-2009 (OR = 1.08, 95% CI: 1.02-1.14) may be the risk factors of liver cancer death. Conclusion The death rate of liver cancer in Xiamen residents remains at a high level. We should not relax our vigilance. We should focus on the rural, male and elderly population and strengthen the prevention and treatment of liver cancer.