论文部分内容阅读
短寿命放射性核素~(11)C、~(13)N、~(15)O、~(18)F都是缺中子型核素,产生β湮没辐射,从而产生方向相反,角度为180°±0.25°的两个511keV的γ光子,具有高灵敏度、高分辨率的正电子发射型计算机断层(PECT),可采用符合线路进行探测。由于~(11)C、~(13)N、~(15)O是人体组织、天然与合成药物的组成元素,而~(18)F则可代替H、卤素、OH基而不改变药物的生物活性,因此,这类药物可研究其在体内的生理、生化、病理过程,其显像不仅是形态型而且是功能性的;不是二维平面显像而是三维立体显像。
Short-lived radionuclides ~ (11) C, ~ (13) N, ~ (15) O and ~ (18) F are all neutron-deficient nuclei that produce beta annihilation radiation, resulting in opposite directions of 180 Two 511 keV gamma photons of ± 0.25 °, with high-sensitivity, high-resolution positron emission computed tomography (PECT), can be detected in line with the line. Because ~ (11) C, ~ (13) N and ~ (15) O are the constituent elements of human tissues, natural and synthetic drugs, ~ (18) F can replace H, halogen and OH groups without changing the drug Biological activity, therefore, these drugs can be studied in vivo physiological, biochemical, pathological process, its imaging is not only morphological but also functional; not two-dimensional planar imaging but three-dimensional imaging.