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目的探讨Ⅰ类切口手术围手术期预防性用药的合理性。方法随机抽取2012年1月～6月份我院Ⅰ类切口手术出院病历200份,对围手术期用药指征、抗菌药物品种选择、用药时间和药物利用指数等方面进行分析。结果 200例Ⅰ类切口手术病历全部使用抗菌药物,使用频度较高的药物为头孢西丁、头孢曲松、五水头孢唑啉,73%的患者用药时间>3天,8%的患者二联、三联用药,使用频度较高的头孢曲松、五水头孢唑啉、头孢呋辛的药物利用指数(DUI)>1。结论Ⅰ类切口手术围手术期预防用药存在较多问题,应进一步规范抗生素的临床应用。
Objective To investigate the rationality of prophylactic prophylaxis perioperatively in class Ⅰ incision. Methods A total of 200 medical records of type Ⅰ incision surgery in our hospital from January to June 2012 were randomly selected and analyzed in terms of perioperative indications, selection of antimicrobial agents, medication duration and drug utilization index. Results All the 200 class I incision surgeries used antimicrobial agents. Cefotaxime, ceftriaxone and cefazolin were the most frequently used drugs in the 200 cases. The medication duration was> 3 days in 73% of the patients and 8% of the patients in the second (DUI)> 1 for ceftriaxone, pentaflumizine pentafluoride and cefuroxime with higher frequency of use. Conclusion There are many problems in the perioperative prophylaxis of class Ⅰ incision. The clinical application of antibiotics should be further regulated.