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目的:评价薄层液基细胞学(Thinprep cytologytest,TCT)检测技术对宫颈癌前病变的诊断和宫颈癌筛查的准确性及临床价值。方法:收集分析2009年5月～2010年11月在我院妇科门诊行TCT检查的受检者7340例,以细胞学诊断为未明确意义的不典型鳞状上皮细胞(ASC-US)及以上者为阳性结果,并对阳性结果行病理组织学诊断,以组织学诊断作为金标准。结果:液基细胞学标本满意度高,对SCC、HSIL、LSIL的准确率分别为76.8%、97.3%、100%。结论:TCT结合TBS诊断系统是目前诊断宫颈癌前病变和筛查宫颈癌的理想方法,同时也可以作为一项宫颈癌术后随访的检测指标。ASC-US患者中存在部分年轻的高危癌前病变者。
Objective: To evaluate the accuracy and clinical value of Thinprep cytology test (TCT) in the diagnosis of cervical precancerous lesions and cervical cancer screening. Methods: A total of 7340 subjects who underwent gynecological outpatient TCT examination in our hospital from May 2009 to November 2010 were collected and analyzed. The results of cytological diagnosis of atypical squamous cell (ASC-US) with undetermined significance and above Who are positive results, and the positive results of histopathological diagnosis of histological diagnosis as the gold standard. Results: The liquid-based cytology specimens were highly satisfactory. The accuracy rates of SCC, HSIL and LSIL were 76.8%, 97.3% and 100% respectively. Conclusion: TCT combined with TBS diagnostic system is the ideal method for the diagnosis of cervical precancerous lesions and screening of cervical cancer, but also can be used as a detection indicator of postoperative follow-up of cervical cancer. There are some young, high-risk precancerous lesions in ASC-US patients.