Promoting effect of ethanol on the synthesis of N-(2-methylphenyl)-hydroxylamine from o-nitrotoluene

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The promoting effect of ethanol on the synthesis of N-(2-methylphenyl)hydroxylamine from o-nitrotoluene in Zn/H2O/CO2 system was observed. By adding appropriate amount of ethanol, the selectivity of N-(2-methylphenyl)hydroxylamine increased from 71 % to 90% when the reduction was carried out at 25 ℃ under normal pressure of CO2.
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