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维生素丙为粉狀或粉狀的結晶,其性质不安定,不能用一般的方法製片,因乾燥顆粒時會破壞,會變色。一般藥剂學上对此种片劑歸納起來有三種作法: 一、混入顆粒中壓——將賦形劑作成顆粒,臨壓時加入药物;二,預壓法製片——藥物與賦形劑細粉混勻后,在壓片機上壓成不十分成形的大片子,將其磨碎成顆料狀后再壓即得;三、濕法作顆粒30℃以下乾燥——將乾燥的溫度降低,以減少作顆粒时藥物的破坏与變質。這三種方法都曾用於正式生產,而以最後一種方法的結果較好。
Vitamin C is powdery or powdery crystalline, its nature is not stable, can not be produced by ordinary methods, because the dry particles will be destroyed, will change color. In general pharmacy, there are three ways to summarize this type of tablet: First, mixing in the granule medium pressure - make the excipients into granules, and add drugs when there is pressure; Second, the pre-pressure tablet - drugs and shaping After the fine powder is mixed, it is pressed on the tablet machine to form a large piece that is not fully formed, and then ground into a granular material and then pressed. That is, the wet method is used to dry the particles below 30° C.—dry. The temperature is lowered to reduce the destruction and deterioration of the drug when used as particles. All three methods were used for formal production, and the results of the last method are better.