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甾体激素要发挥作用必须先与靶细胞中的胞浆受体结合,再发生一系列细胞内反应,最后产生生物学效应。激素受体是激素发生作用必不可少的中间物质。许多研究业已证明胞浆雌激素受体(ERc)及孕激素受体(PRc)的浓度可以提示复发或转移的乳腺癌或子宫内膜癌的内分泌治疗效果。在有条件的单位乳癌组织的ERc测定已作为常
Steroid hormones to play a role must first target cells in the cytoplasmic receptor binding, and then a series of intracellular reactions, and finally have a biological effect. Hormone receptors are essential intermediates in the role of hormones. Many studies have demonstrated that the concentrations of cytoplasmic estrogen receptor (ERc) and progesterone receptor (PRc) can indicate the endocrine therapeutic effect of recurrent or metastatic breast or endometrial cancer. ERc determination of breast cancer tissue in the conditional unit has been used as usual