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目的:探讨血清钙对帕金森患者认知水平的影响。方法:收集2013年12月至2016年12月来天台县人民医院就诊的89例帕金森病患者为研究对象,依据患者的认知、运动功能及抑郁评分将所选的89例帕金森病患者分为非痴呆组与痴呆组,同时选取同时期50名健康人为对照组,然后对三组研究对象的认知功能相关因素、血钙进行分析与比较。结果:痴呆组患者的血钙水平明显低于非痴呆组与对照组,而非痴呆组与对照组两组间的差异不大。血钙水平、Hoehn-Yahr分期(H—Y分期)、帕金森病综合量表Ⅲ(UPSDRSⅢ)及教育水平与帕金森病患者的认知功能有相关性。血清钙及受教育程度是帕金森病患者认知功能的独立危险因素。结论:血清钙水平可作为协助判断帕金森病患者认知水平的一个简易指标,血清钙水平对帕金森病患者的认知水平有预测价值。
Objective: To investigate the effect of serum calcium on the cognition of Parkinson’s disease patients. Methods: A total of 89 patients with Parkinson’s disease from TEDA People’s Hospital from December 2013 to December 2016 were enrolled in this study. Based on the patients’ cognition, motor function and depression score, 89 patients with Parkinson’s disease Divided into non-dementia group and dementia group. At the same time, 50 healthy people in the same period were selected as the control group. Then the related factors of cognitive function and serum calcium in the three groups were analyzed and compared. Results: The level of serum calcium in patients with dementia was significantly lower than that in non-dementia and control groups, but not in dementia group and control group. Blood calcium levels, Hoehn-Yahr staging (H-Y staging), Parkinson’s disease comprehensive Table III (UPSDRS III), and educational level were associated with cognitive function in patients with Parkinson’s disease. Serum calcium and education level are independent risk factors for cognitive function in patients with Parkinson’s disease. Conclusion: Serum calcium level can be used as a simple index to help determine the cognitive level of patients with Parkinson’s disease. Serum calcium level has predictive value for the cognitive level of patients with Parkinson’s disease.