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目的观察曲美布汀联合复方消化酶治疗功能性消化不良的临床疗效。方法将110例功能性消化不良患者随机分为3组:曲美布汀治疗组(A组,32例)、复方消化酶治疗组(B组,36例)和曲美布汀联合复方消化酶治疗组(C组,42例),均连续用药4周,比较治疗后的临床疗效和总有效率。结果C组患者治疗后临床疗效与A、B组比较,差异均有统计学意义(P<0.05)。治疗后A、B、C组患者总有效率分别为71.9%、72.2%、92.9%,C组总有效率与A、B组比较,差异均有统计学意义(P<0.05)。结论曲美布汀联合复方消化酶治疗功能性消化不良的疗效显著高于单纯曲美布汀或复方消化酶治疗。
Objective To observe the clinical efficacy of trimebutine combined with compound digestive enzymes in the treatment of functional dyspepsia. Methods One hundred and ten patients with functional dyspepsia were randomly divided into three groups: trimebutine treatment group (A group, 32 cases), compound digestive enzyme treatment group (B group, 36 cases) and trimebutine combined with compound digestive enzyme Treatment group (C group, 42 cases), were continuous medication for 4 weeks, compared the clinical efficacy and total effective rate after treatment. Results After treatment, the clinical efficacy of group C was significantly different from that of group A and B (P <0.05). After treatment, the total effective rates of patients in group A, B and C were 71.9%, 72.2% and 92.9%, respectively. The total effective rate in group C was significantly higher than that in group A and B (P <0.05). Conclusion Trimebutine combined with compound digestive enzyme treatment of dysfunctional dysfunction was significantly higher than trimebutine alone or compound digestive enzyme therapy.