乙醇胺盐酸盐以凡士林为介质,加入0.45分子比的氯化胺为催化剂,于250—270℃环化反应6小时,可得高产率的盐酸胡椒嗪。以工业混合乙醇胺为原料,经过环化制成盐酸胡椒嗪,加碱中和后进行蒸馏,得到六水胡椒嗪。由氯乙醇开始至六水胡椒嗪收率可达65.35％,较之不用催化剂可提高6—7％.如在氯乙醇胺化所得的乙醇胺溶液中,加入一 Ethanolamine hydrochloride with petroleum jelly as the medium, adding 0.45 molecular amine chloride as a catalyst, and cyclization reaction at 250-270 DEG C for 6 hours, yielding high yield of piperzine hydrochloride. Industrial mixed ethanolamine as raw material, after cyclization made of piperzine hydrochloride, alkali and after the distillation, get hexachlorprorate. Starting from chloroethanol to hexachlorproperazine yield up to 65.35%, compared with no catalyst can be increased by 6-7% .As in the ethanol amine amine obtained by the solution of ethanolamine, adding a