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对施行心脏手术后低心排的２５名患者分为两组，分别静脉注射两种剂量的氨吡酮，观察该药对患者的血液动力学影响。结果表明５例显效、１９例有效、１例因血压下降而终止用药。用药后两组ＣＩ、ＣＯ均较用药前显著增加，在连续观察中，均能保持在已增高的水平上，且与剂量无明显相关。同时ＰＣＷＰ迅速下降，较用药前有显著差异。研究揭示氨吡酮可作为治疗心脏手术后低心排的首选药物。
Twenty-five patients with low cardiac output after cardiac surgery were divided into two groups. Two doses of amiloride were injected intravenously to observe the hemodynamic effects of the drug on the patients. The results showed that 5 cases markedly effective in 19 cases, 1 case of termination of medication due to decreased blood pressure. After treatment, the CI and CO in both groups increased significantly compared with those before treatment, and were maintained at an elevated level in continuous observation without any significant correlation with the dosage. At the same time PCWP decreased rapidly, compared with before treatment were significantly different. Studies have shown that pymiroprid can be used as the preferred drug for the treatment of low cardiac output after cardiac surgery.