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目的探讨超声造影软件SonoLiver CAP对常规超声检查阴性的前列腺癌的诊断价值。方法对82例血清前列腺特异性抗原(PSA)升高(≥4.00 ng/ml)而常规超声检查阴性的患者在穿刺前行经直肠前列腺超声造影检查,观察前列腺最大横切面下双侧外腺区的灌注模式,并对双侧外腺利用SonoLiver CAP软件做灌注时间-强度曲线,分析比较双侧外腺的造影参数差异。结果 82例患者穿刺病理诊断为前列腺癌患者33例,前列腺增生者49例。双侧外腺区均穿刺阳性的前列腺癌及前列腺增生组,双侧外腺超声造影各参数比较(IMAX、RT、TTP和mTT)未见显著差异;Gleason评分<7的单侧外腺区穿刺阳性的前列腺癌,双侧外腺超声造影各参数间(IMAX、RT、TTP和mTT)未见显著差异;Gleason评分=7的单侧外腺穿刺阳性的前列腺癌,癌灶侧外腺RT和TTP均显著低于对侧正常外腺区,IMAX和mTT双侧外腺未见显著差异。结论采用SonoLiver CAP超声造影定量分析软件,对常规超声检查阴性的前列腺癌,能更好地反映前列腺癌双侧外腺区灌注特征,具有一定的临床应用价值。
Objective To investigate the diagnostic value of SonoLiver CAP in the ultrasound-negative prostate cancer. Methods Eighty-two patients with elevated serum PSA (≥4.00 ng / ml) who underwent conventional ultrasonography before transanal prostatic ultrasonography were examined by biopsy to observe the changes in bilateral extra-gland regions Perfusion pattern, and the bilateral outer gland using SonoLiver CAP perfusion time-intensity curve, analysis and comparison of bilateral gonadal differences in imaging parameters. Results 82 cases of pathological diagnosis of prostate cancer in 33 patients with prostate cancer, 49 cases of benign prostatic hyperplasia. There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups in terms of ITA, TTP and mTT Positive prostate cancer and bilateral extracorporeal ultrasound (IMAX, RT, TTP and mTT) were not significantly different; Gleason score = 7 of unilateral epipuncture-positive prostate cancer, foci lateral gland RT and TTP were significantly lower than the contralateral normal outer gland, IMAX and mTT bilateral outer no significant difference. Conclusions SonoLiver CAP ultrasonography quantitative analysis software has a certain clinical value for the prostate cancer patients with negative negative results of conventional ultrasound.